Melanotan-2 (MT-2)

Name: Melanotan-2 (MT-2)
Brand: Reliable Research Labs
SKU: MT2
Price: 29.99 GBP
Availability: InStock

£29.99

Melanotan-2 (MT-2) is a synthetic cyclic analogue of α-MSH, supplied here as a 10 mg vial of lyophilised powder tested to ≥99.6% purity by HPLC analysis. Unlike Melanotan-1 (afamelanotide), which is comparatively MC1R-selective, MT-2 is a non-selective melanocortin-receptor agonist activating MC1R, MC3R and MC4R, giving it a broader research scope spanning melanogenesis, energy-balance signalling, and sexual-arousal pathways. MT-2 is structurally and pharmacologically distinct from PT-141 (bremelanotide), a related but separate compound later developed from this research area. Reliable Research Labs supplies Melanotan-2 from the UK strictly for qualified laboratory research — see "About Melanotan-2 (MT-2)" below for further background.
FOR LABORATORY RESEARCH USE ONLY

Not Intended for Human or Animal Consumption

View Certificate of Analysis (COA)

PRODUCT SPECIFICATIONS

Quantity: 10 mg
Appearance: Lyophilized (Freeze-Dried) Powder
Purity: ≥99.6% (Confirmed by HPLC Analysis)

RESEARCH USE

This material is supplied exclusively for laboratory-based, in vitro research conducted by qualified professionals. It is not approved for use in humans or animals and must not be incorporated into pharmaceuticals, dietary supplements, food products, cosmetics, or diagnostic applications.

IMPORTANT NOTICE

This product has not been reviewed or approved by the U.S. Food and Drug Administration (FDA). No claims are made regarding safety, efficacy, or therapeutic benefit. It is not intended to diagnose, treat, cure, or prevent any medical condition. Researchers are responsible for ensuring all work complies with applicable laws, regulations, and institutional protocols.

PURCHASE AGREEMENT

By completing a purchase, the customer confirms that they are a qualified researcher, laboratory, educational institution, or authorized organization purchasing this product solely for lawful research purposes. The purchaser accepts full responsibility for the proper storage, handling, use, and disposal of the product, as well as compliance with all applicable local, state, and federal regulations. All sales are considered final unless otherwise stated.

About Melanotan-2 (MT-2)

Melanotan-2 (MT-2) is a synthetic cyclic analogue of α-MSH (alpha-melanocyte-stimulating hormone) — a lactam-bridged heptapeptide structurally distinct from the naturally occurring linear α-MSH molecule. Unlike Melanotan-1 (afamelanotide), which is comparatively selective for the melanocortin-1 receptor (MC1R), MT-2 is a non-selective melanocortin-receptor agonist, activating MC1R alongside other melanocortin receptor subtypes including MC3R and MC4R.

This broader receptor activity is the key distinction between MT-2 and MT-1: MT-2's research interest extends beyond MC1R-mediated melanogenesis into MC4R-related signalling, which is implicated in both energy-balance/appetite regulation and sexual-arousal pathways in the research literature.

MT-2 also has a notable historical connection to PT-141 (bremelanotide): PT-141 was identified during MT-2-related melanocortin research as a more MC4R-selective derivative, later developed separately as its own distinct compound. MT-2 and PT-141/bremelanotide remain structurally and pharmacologically distinct and should not be treated as interchangeable.

Reliable Research Labs supplies Melanotan-2 (MT-2) as a 10 mg vial of lyophilised powder, tested to ≥99.6% purity by HPLC analysis, strictly for qualified laboratory research. See our Compound Library entry for Melanotan-2 for a wider overview.

What Effects of Melanotan-2 Are Studied?

Because MT-2 activates multiple melanocortin receptors rather than MC1R alone, its research literature spans several distinct areas. MC1R-mediated research has examined melanogenesis (melanin production) and pigmentation responses, similar in principle to Melanotan-1 research, though MT-2's broader receptor activity means findings are not directly interchangeable between the two compounds.

MC4R-related research has examined MT-2 in connection with energy-balance and appetite-regulation signalling in animal models, and separately in connection with sexual-arousal responses in both preclinical and limited early human experimental research — the research interest that eventually led to the development of PT-141/bremelanotide as a more selective compound for that specific pathway.

Evidence quality varies considerably across these research areas: melanogenesis research includes both animal and some human experimental data, while appetite and sexual-arousal research is predominantly preclinical, with human experimental findings that are limited in scale and not equivalent to confirmed clinical outcomes.

MT-2 is widely discussed online in connection with tanning, libido, and appetite suppression, but these are not established, guaranteed outcomes of this research product. Reliable Research Labs supplies Melanotan-2 exclusively for qualified laboratory research. Nothing on this page describes, recommends or implies dosing, administration, tanning protocols, or any cosmetic, sexual, appetite-related, or medical outcome from using this product.